5-Amino-1MQ
5-Amino-1MQ is a small molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), extensively researched for its effects on cellular metabolism and weight management.
- Category
- Weight Loss Peptides
- Purity
- 99.6%
- Price
- from $213.00
- Availability
- In stock
- Size
- 50mg
- CAS number
- 42464-96-0
- Molecular formula
- C₁₁H₁₄N₂ (MW: 174.24 g/mol)
- Storage
- Store lyophilized powder at -20°C in a dry, light-protected environment. After reconstitution, store at 2–8°C and avoid repeated freeze-thaw cycles.
- Half-life
- Estimated to be rapid, dependent on administration route
About 5-Amino-1MQ
5-Amino-1MQ (5-amino-1-methylquinolinium) is a highly selective, membrane-permeable small molecule that acts as an inhibitor of nicotinamide N-methyltransferase (NNMT). NNMT is an enzyme predominantly found in adipose tissue that plays a critical role in cellular energy metabolism. By inhibiting NNMT, 5-Amino-1MQ prevents the depletion of NAD+, leading to an increase in cellular NAD+ levels, which subsequently boosts sirtuin-1 (SIRT1) activity and increases basal metabolic rate.
In preclinical models, 5-Amino-1MQ has demonstrated the ability to reduce diet-induced obesity without affecting food intake, suggesting it alters cellular energy expenditure pathways. It is widely investigated as a potential therapeutic agent for metabolic syndrome, obesity, and age-related metabolic decline.
Store in a cool, dry environment: Store lyophilized powder at -20°C. After reconstitution, refrigerate at 2–8°C.
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5-Amino-1MQ Certificate of Analysis · All research peptides
For laboratory research use only. Not for human consumption.